Labels:text | screenshot | black and white | black | font | document OCR: a direct Ketoconazole inhibits cortisol synthesis It is action on the P450 cytochrome enzymes lthough generally well tolerated (400-800mg/d), hepatotoxicity is an occasional problem. ds poorly toDisseminated adrenal carcinoma respon lled by any therapy but can sometimes be contr doses, large doses (4-10g/d) of o,p-DDD: at these d ataxia, unpleasant side effects, such as nausea a doses are common. In Cushing's disease, lowe medical (1-3g/d) may be successfully used in the ug takes management without side effects. The d aises six weeks to be fully effective and often circulating lipid levels. See also: · Steroid Biosynthesis - Ketoconazole